We can arrange an endometrial scratch.
Unsuccessful IVF is difficult to accept but is not uncommon. Embryo implantation is a complex process and some common causes of failure can be due to poor endometrial lining (endometrium) or a genetically abnormal embryo. Women who have repeatedly failed IVF despite apparently good quality embryos may be candidates for the latest IVF treatment called endometrial scratching which has been shown in several randomised studies to improve (even double) the implantation rate in women who have had repeated failures.
The process of endometrial scratching as it relates to embryo implantation is not entirely understood and some questions still remain unanswered. Scientists involved in studies believe that there may be two reasons for the increased implantation rates:
- Increase of endometrial white blood cells. It appears that endometrial injury increases the production of white blood cells which secrete so called growth factors which in turn control embryo implantation.
- Gene switching within the endometrium. Scientists speculate that sometimes embryos fail to implant due to genetic switching related to endometrial receptivity. That is, genes responsible for implantation of embryos are not switched on during the time when embryos are supposed to implant. Endometrial scratching may increase expression of genes (switching of genes) thought to be responsible for preparation of endometrium for implantation.
The procedure is carried out in the luteal phase of the cycle (i.e. after ovulation) before your treatment. Normally this is done around day 21 of the cycle. The procedure is carried by a doctor. You are advised to take analgesia 1-2 hours before your scheduled procedure e.g. ibuprofen (e.g. nurofen) or diclofenac (e.g. voltarol)providing these are not contraindicated.
Contact us in confidence, for a free consultation about our fertility support services or to arrange an Endometrial Scratch referral.